The ISS Impact Report 2023–2024 covers two years of social impact by the International Social Service, protecting children and families across borders since 1924. This report underlines ISS activities in Cross-Border Social Casework, Network Development and Training, Advocacy and Alternative Care. It also highlights the achievements of the ISS International Reference Center for the rights of children deprived of their family. Finally, our two-year report has a special focus on our centennial celebrations and activities, and the ISS International Conference ‘Throughout time, across borders’ organised during the week of 7th of October 2024.